Initial responses to questionnaires used to assess participants' understanding of informed consent for malaria vaccine trials conducted in the United States and Mali were tallied. Total scores were analyzed by age, sex, literacy (if known), and location. Ninety-two percent (92%) of answers by United States participants and 85% of answers by Malian participants were correct. Questions more likely to be answered incorrectly in Mali related to risk, and to the type of vaccine. For adult participants, independent predictors of higher scores (...) were younger age and female sex in the United States, and male sex in Mali. Scores in the United States were higher than in Mali (P = 0.005). Despite this difference participants at both sites were well informed overall. Although interpretation must be qualified because questionnaires were not intended as research tools and were not standardized among sites, these results do not support concerns about systematic low understanding among research participants in developing versus developed countries. (shrink)

In this note we present a three-valued intensional logic, which is an extension of both Montague's intensional logic and ukasiewicz three-valued logic. Our system is obtained by adapting Gallin's version of intensional logic (see Gallin, D., Intensional and Higher-order Modal Logic). Here we give only the necessary modifications to the latter. An acquaintance with Gallin's work is pressuposed.

IGM form a unified group and we denote their consensus by the sign Z; in the absence of I we signify the consensus of GM with £. It will be seen that in the earlier part of Book I this family is reduced to M. Here one may sometimes call on the help of Harleianus 2564 saec. xv, which we call h; this manuscript, though overlaid with the vulgate text, shows a number of striking readings which reveal a source closely (...) related to G. At the end of the poem we lack the guidance of A, which, though not free from interpolations, is by far the most sincere witness; here the testimony of Cantabrigiensis Pembrokianus 280 saec. xii, which we call F and which in the earlier books shows more fidelity to the A-tradition than any other manuscript, is sometimes useful, though it cannot be relied on without grave reservations. Editors usually quote Monacensis 8122 as if it were a primary witness; it is nothing of the sort, but rather a much corrupted and interpolated offshoot of the A-tradition diluted by some contamination from Z. We use ω to indicate the mass of the vulgar manuscripts and ς to indicate some of them. (shrink)

The Thebaid is not easy reading, and copyists have not helped to make it easier. There are many pitfalls in the language of Statius, and words cannot be taken always at their face value. I have erred myself and suffered. It may be of interest to give a few instances.

Upshot: In our response we focus on five questions that point to important common themes in the commentaries: why start in wicked problems, what kind of system is a scientific perspective, what is the nature of second-order research processes, what does this mean for understanding interdisciplinary work, and how may polyocular research help make real-world decisions.

Upshot: In our response we focus on how different types of systems are related from a constructivist perspective, and specifically on the relation between communicational social systems and embodied agency.

Open peer commentary on the article “Social Autopoiesis?” by Hugo Urrestarazu. Upshot: We agree on the need to explore a concept of social autopoiesis that goes beyond a strictly human-centered concept of social systems as autopoietic communicative systems. But both Hugo Urrestarazu and Niklas Luhmann neglect the importance of semiosis in understanding communication, and this has important implications for the question of a more general approach to social systems.